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Immune cell populations before and after treatment with NACT, stratified by the tumor (a,c) and stromal (b,d) compartments. To increase visibility, small cell populations were stratified and scaled up. Effector (CD8+), regulatory (FOXP3+) and helper (CD3+CD8-FOXP3-) (a,c) T-cells are shown separately from overall T-cell (CD3+) and macrophage (CD68+) populations to enhance visual comparison.
