Table 3.
Concentrations of SASP-Related Cytokines in the AqH
| Cytokine (pg/mL) | APAC | ARC | P Value* |
|---|---|---|---|
| IL-1α | 44.0476 ± 39.997 | 20.7273 ± 21.994 | 0.052 |
| IL-1β | 43.176 ± 25.679 | 44.877 ± 29.714 | 0.991 |
| IL-6 | 2880.57 ± 1070.996 | 101.77 ± 106.973 | <0.0001 |
| IL-8 | 788.38 ± 553.431 | 164.95 ± 146.456 | <0.0001 |
| IL-13 | 0 | 0 | 1.000 |
| TNF-α | 551.4 ± 440.9155 | 159.6 ± 119.164 | <0.0001 |
| GM-CSF | 8.1429 ± 12.167 | 7.3636 ± 8.301 | 0.068 |
| CCL-2 | 282.81 ± 211.254 | 145.50 ± 121.791 | 0.008 |
| CCL-20 | 0 | 0 | 1.0 |
| MCP-1 | 1739.48 ± 1185.390 | 316.36 ± 328.621 | <0.0001 |
| MCP-3 | 0 | 0 | 1.0 |
| GROα | 75.2381 ± 39.319 | 33.4545 ± 17.965 | <0.0001 |
| MIP-1α | 14.62 ± 16.566 | 9.05 ± 10.513 | 0.048 |
| VEGF-α | 1305.1905 ± 789.831 | 260.9091 ± 347.151 | <0.0001 |
| IGFBP2 | 78.48 ± 44.539 | 53.45 ± 30.709 | 0.061 |
| IGFBP4 | 0 | 0 | 1.000 |
| IGFBP5 | 3084.95 ± 1303.561 | 166.09 ± 160.008 | < 0.0001 |
| IGFBP6 | 0 | 0 | 1.000 |
| IGFBP7 | 410.5 ± 181.906 | 132.6 ± 105.121 | <0.0001 |
| TGF-β1 | 3057.10 ± 1418.243 | 302.23 ± 260.093 | <0.0001 |
| HGF | 35.9524 ± 29.889 | 28.8636 ± 23.526 | 0.450 |
| MMP-1 | 6.95 ± 8.488 | 10.68 ± 11.582 | 0.340 |
| MMP-3 | 19.43 ± 20.356 | 10.55 ± 13.415 | 0.159 |
| MMP-4 | 0 | 0 | 1.000 |
| MMP-10 | 81.19 ± 38.798 | 40.50 ± 21.743 | <0.0001 |
HGF, hepatocyte growth factor.
*
Significance of differences between groups: Mann–Whitney U-test. Bold values represent significance.