Table 4.

Correlation Between Oxidative Stress Markers and SASP Cytokine Levels in APAC Patients

	ROS		8-OHdG		MDA		SOD		GSH/GSSG Ratio
Cytokine (pg/mL)	r	P Value*	r	P Value*	r	P Value*	r	P Value*	r	P Value*
IL-1α	0.005	0.984	0.314	0.166	–0.101	0.664	0.131	0.571	0.084	0.718
IL-6	0.630	0.002	0.369	0.100	0.566	0.007	–0.550	0.010	–0.562	0.008
IL-8	0.768	<0.0001	0.348	0.122	0.381	0.089	–0.677	0.001	–0.553	0.009
TNF-α	–0.061	0.793	0.023	0.922	0.256	0.263	–0.194	0.400	–0.086	0.712
CCL-2	0.560	0.008	0.309	0.173	0.291	0.201	–0.558	0.009	–0.693	<0.0001
MCP-1	0.404	0.069	0.368	0.101	0.262	0.251	–0.081	0.729	–0.328	0.147
GROα	0.455	0.038	0.255	0.264	0.408	0.066	–0.407	0.067	–0.467	0.033
MIP-1α	0.542	0.011	0.118	0.612	0.220	0.338	–0.368	0.101	–0.485	0.026
VEGF-α	0.171	0.457	0.109	0.640	0.038	0.871	0.012	0.960	–0.336	0.137
IGFBP5	0.733	<0.0001	0.361	0.107	0.484	0.026	–0.783	<0.0001	–0.639	0.002
IGFBP7	0.597	0.004	0.246	0.282	0.449	0.041	–0.609	0.003	–0.466	0.033
TGF-β1	0.653	0.001	0.481	0.027	0.525	0.015	–0.576	0.006	–0.613	0.003
MMP-10	–0.303	0.182	–0.277	0.224	–0.146	0.527	0.056	0.809	0.205	0.373

^*Significance of differences between groups: Spearman's rank-order correlation analysis. Bold values represent significance.