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. 2022 Jan 24;11(1):33. doi: 10.1167/tvst.11.1.33

Table.

Prolonged Local Anesthesia of the Cornea and Control (Normal)

Group Duration of Complete Block Mean ± SD (Hours) Time to Return of Normal Sensation Mean ± SD (Hours) Keratopathy Present Number of Corneas
Retrobulbar PLA: PGS-TTX with lubrication* 50.1 ± 3.6 55.1 ± 3.6 0/12
Retrobulbar PLA: PGS-TTX without lubrication* 46 ± 2 48 1/4
PLA: Topical amitriptyline without lubrication* 24 24 12/12
PLA: Topical amitriptyline with lubrication* 24 24 4/4
Untreated/normal cornea 0 0 0/12
*

Lubricating eye drops.

Block duration was truncated by euthanasia.