Table 2.
Patient number | Age | Primary cancer | Prior RT dose, median, Gy/fx | Interval to reRT,mo | ReRT location | ReRT PTV, cm3 | ReRT total dose/ fx | ReRT schedule | ReRT EQD210, median, Gy | ReRT EQD23, median, Gy | On-table adaptive replanning | Concurrent chemotherapy | Local progression | Grade ≥3 toxic effects |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 88 | Pancreas | 30/5 | 12.8 | Pancreas | 31.31 | 25/5 | QD | 31.3 | 40 | No | No | No | No |
2 | 58 | Rectum | 50.4/28 | 30.1 | Presacral | 160.71 | 54/36 | bid | 51.8 | 48.6 | No | Xeloda | 21.9 mo after reRT | No |
3 | 62 | Rectum | 45/25 | 26.8 | LN | 33.24 | 40.8/34 | bid | 38.1 | 34.3 | No | Xeloda | 32.3 mo after reRT | No |
4 | 60 | Lung | 40/5 | 7.6 | LN | 43.4 | 40/5 | QD | 60 | 88 | Yes | No | No | No |
5 | 70 | Pancreas | 59.4/33 | 11.9 | Pancreas | 190.2 | 50/5 | QD | 83.3 | 130 | Yes | No | No | No |
6 | 34 | Rectum | 58.8/28 | 59.0 | Presacral | 38.84 | 42/28 | bid | 40.3 | 37.8 | No | Xeloda | 8 mo after reRT | No |
7 | 42 | Cervix | 59.4/33 | 31.4 | LN | 28.34 | 33/6 | QD | 42.6 | 56.1 | Yes | No | No | No |
8 | 62 | Cervix | 59.4/33 | 10.7 | LN | 26.26 | 32.5/5 | QOD | 44.7 | 61.8 | No | No | No | No |
9 | 76 | Pancreas | 50.4/28 | 13.7 | Pancreas | 37.84 | 40/5 | QD | 60 | 88 | No | No | No | No |
10 | 80 | Rectum | 50.0/25 | 43.4 | Rectum | 143.45 | 42/28 | bid | 40.3 | 37.8 | No | Xeloda | No | No |
11 | 78 | Bile duct | 56/28 | 32.4 | SMA | 53.25 | 40/6 | QOD | 55.6 | 77.3 | No | No | No | No |
Abbreviations: bid = twice daily; EQD2 = equivalent dose in 2-Gy fractions; fx = fraction; LN = lymph node; PTV = planning target volume; QD = daily; QOD = every other day; reRT = reirradiation; RT = radiation therapy.