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. 2022 Jan 17;12:819482. doi: 10.3389/fphar.2021.819482

TABLE 2.

Jadad scale of the included trials.

Author year JADAD
a b c D T
Heber et al. (1999) 1 1 2 1 5
Zhao et al. (2003) 1 1 2 0 4
Lin et al. (2005) 1 1 2 1 5
Becker et al. (2009) 2 2 1 1 6
Yang et al. (2009) 1 1 1 1 4
Bogsrud et al. (2010) 1 1 2 1 5
Halbert et al. (2010) 2 2 2 1 7
Karl et al. (2012) 2 2 1 1 6
Cicero et al. (2013) 2 2 1 1 6
Verhoeven et al. (2013) 2 1 2 1 6
Moriarty et al. (2014) 2 2 2 1 7
Cui et al. (2015) 1 1 1 1 4
Wang et al. (2015) 1 1 1 1 4
Heinz et al. (2016) 1 1 2 1 5
Cicero et al. (2017) 2 2 2 1 7

From a to d, dimension of the Jadad scale. Points awarded: a, study was described as randomized, 1 point; the method was appropriate (table of random numbers, computer generated, etc.), 2 points; b, study used allocation concealment, 1 point; the method was appropriate (taken by the third one who wasn’t researcher or patient, opaque envelope, etc.), 2 points; c, study was described as double blind, 1 point; the method was appropriate (identical placebo, active placebo, dummy, etc.), 2 points; d, study reported withdraws and dropouts and described the reasons. T, total.