TABLE 1.
Plasma level of interleukin 10 (IL-10) on days 0, 14, and 28 in spontaneously hypertensive rats (SHR): adult SHR receiving oral treatment with epoxyeicosatrienoic acid analog at a dose of 10 mg/kg/day (EET-A) or 40 mg/kg/day (EET-A HD) and young SHR treated with epoxyeicosatrienoic acid analog (EET-A) alone or combined with AAA, a 20-hydroxyeicosatetraenoic receptor antagonist (EET-A + AAA), both at a dose of 10 mg/kg/day.
| IL-10 (pg/ml) | Day 0 | Day 14 | Day 28 | |
| Adult SHR | EET-A | 70 ± 12 | 56 ± 14 | 54 ± 12 |
| EET-A HD | 58 ± 10 | 53 ± 14 | 54 ± 10 | |
| Control | 72 ± 13 | 56 ± 15 | 74 ± 19 | |
| Young SHR | EET-A | 68 ± 16 | 42 ± 6 | 34 ± 5 |
| EET-A + AAA | 57 ± 15 | 48 ± 9 | 39 ± 9 | |
| Control | 44 ± 10 | 56 ± 7 | 72 ± 13 |
Values are expressed as means ± SEM (n = 6 in each group); not significant.