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Schematic presentation of diacerin antineoplastic effect. Diac: Diacerein; IL-6: interleukin-6; K-Ras: Kirsten rat sarcoma viral oncogene; NICD: Notch intracellular domain; MMP-9: matrix metalloproteinase-9; NF-κB: nuclear factor-kappa B; VEGF: vascular endothelial growth factor; GSK3-β: glycogen synthase kinase 3-β; p-Akt: phosphorylated protein kinase B.
