Figure 4.

Adipocyte-specific knockout of Nos2 prevents triglycerides, cholesterol, non-esterified fatty acid and glycerol in plasma. Plasma levels of triglycerides (A), total cholesterol (B) non-esterified fatty acids (C) and free glycerol (D). Adipose tissue triglycerides accumulation in inguinal and epididymal adipose tissue (E,F). Two-way ANOVA with a Student-Newman-Keuls post hoc test was applied to calculate the significance of the differences between groups. Data are expressed as the mean ± SEM. n = 11–12 (B,C); n = 10–12 (A,D); n = 8–12 (E,F); ∗p < 0.05, ∗∗p < 0.01 and ∗∗∗p < 0.001 for diet effect; ^#p < 0.05 for genotype difference.