Table 4.

Development of transplant complications in operationally tolerant patients and tolerance biomarker negative liver transplant recipients

	Operationally tolerant (n = 8)	Tolerance biomarker negative (n = 41)	P-value
Renal function (change from baseline;µmol/L)	−10.1 ± 15.1	+0.6 ± 15.3	0.075
Hypertension (new diagnosis)	0 (0%)	3 (7.3%)	0.9
Diabetes (new diagnosis)	0 (0%)	1 (2.4%)	0.9
Malignancy (new diagnosis)	0 (0%)	1 (24%)	0.9
Death	0 (0%)	2 (4.9%)	0.9

Data are presented as mean ± SD or number (percent). Change in clinical parameters since time of enrolment into trial (Phase 1).