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. 2022 Jan 17;12:811833. doi: 10.3389/fgene.2021.811833

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Copyright © 2022 Wang, Zheng, Zhang, Tian, Fang, Qi, Du, Chen, Chen, Li, Shen and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Secondary structure analysis of the COQ6 protein and STRING network analysis. (A) Secondary structure and solvent accessibility of wild-type COQ6 and the protein with the candidate variant (p.Gln461Ter) were analyzed using the PredictProtein online database. (B) The functional association of the COQ6 with other proteins involved in the pathway of CoQ10 biosynthesis was predicted by STRING network analysis (STRING v11.0, https://stringdb.org/).