Table 3.

LS mean change (standard error) from baseline to Week 52 in MFM32 by anchor group.

Anchor	LS mean change on MFM32 total score (% points)
CGI-C (minimally, much and very much improved groups)	3.49 (0.47) (n = 76, mean = 8 years, median = 6 years)
RULM (≥2-points change)	3.11 (0.49) (n = 73, mean = 7 years, median = 6 years)
RULM (≥3-points change)	3.72 (0.56) (n = 53, mean = 7 years, median = 5 years)
SMAIS-ULM CG (≥3-points change)	2.35 (0.58) (n = 51, mean = 9 years, median = 8 years)
EQ-5D-5L CG self-care item (improved by 1 category)	2.88 (0.66) (n = 41, mean = 8 years, median = 6 years)

LS, Least Squares; MFM32, 32-item Motor Function Measure; CGI-C, Clinical Global Impression of Change Scale; RULM, Revised Upper Limb Module; SMAIS-ULM CG, SMA Independence Scale Upper Limb Module Caregiver Report; EQ-5D-5L CG, EuroQol 5D-5L Caregiver Report.