TABLE I.

DIPS-Plus’ effect on the MedAUROC of SOTA algorithms for protein interface prediction.¹

	# GNN Layers
Method	1	2	3	4
NGF [14]	0.865 (0.007)	0.871 (0.013)	0.873 (0.017)	0.869 (0.017)
DTNN [53]	0.867 (0.007)	0.880 (0.007)	0.882 (0.008)	0.873 (0.012)
Node and Edge Average [20]	0.876 (0.005)	0.898 (0.005)	0.895 (0.006)	0.889 (0.007)
NeiA+HOPI [41]	0.902 (0.012)	0.919 (0.015)	0.921 (0.009)	0.915 (0.009)
NeiWA+HOPI [41]	0.908 (0.019)	0.930 (0.016)	0.924 (0.011)	0.914 (0.013)
NeiA+HOPI+DIPS-Plus [42]	0.9426 (0.001)	0.9438 (0.001)	0.9432 (0.005)	0.9426 (0.007)
NeiWA+HOPI+DIPS-Plus [42]	0.9065 (0.029)	0.9342 (0.01)	0.9335 (0.006)	0.9384 (0.004)

¹MedAUROC: median area under the receiver operating characteristic curve. SOTA: state-of-the-art.