Table 4.
Univariable logistic regression | Multivariable logistic regression | ||||||
---|---|---|---|---|---|---|---|
N = 39 | OR | 95%CI | P | OR | 95%CI | P | |
Age | |||||||
52–58 years | 7 (18) | Ref | – | – | – | ||
59–64 years | 14 (35.9) | 1.34 | 0.53–3.38 | 0.53 | – | – | – |
65–78 years | 18 (46.1) | 2.30 | 0.94–5.62 | 0.07 | – | – | – |
Sex (M) | 18 (46.1) | 0.51 | 0.26–0.97 | 0.04 | – | – | – |
Smoking | |||||||
Former smoker | 7 (18) | Ref | – | – | – | ||
Current smoker | 32 (82) | 1.79 | 0.78–4.12 | 0.17 | – | – | – |
Pack year | 52.4 (27.6) | 1.01 | 0.99–1.02 | 0.33 | – | – | – |
Lung nodules | |||||||
No nodules | 11 (28.2) | Ref | Ref | ||||
Nodules < = 8 mm | 11 (28.2) | 0.84 | 0.36–1.96 | 0.68 | 0.77 | 0.33–1.82 | 0.55 |
Nodules > 8 mm | 17 (43.6) | 5.44 | 2.45–12 | < 0.01 | 5.54 | 2.45–12.54 | < 0.01 |
Ground glass opacity | 3 (7.7) | 1.25 | 0.37–4.24 | 0.71 | 1.12 | 0.33–3.83 | 0.86 |
Centrilobular emphysema | 14 (35.9) | 1.30 | 0.66–2.55 | 0.45 | 1.34 | 0.67–2.67 | 0.40 |
Paraseptal emphysema | 6 (15.4) | 1.51 | 0.61–3.72 | 0.37 | 1.49 | 0.59–3.73 | 0.40 |
Atelectasis areas | 6 (15.4) | 1.89 | 0.76–4.69 | 0.17 | 1.92 | 0.76–4.84 | 0.17 |
Bronchial wall thickening | 18 (46.1) | 1.36 | 0.71–2.60 | 0.35 | 1.25 | 0.64–2.42 | 0.51 |
Bronchiectasis | 3 (7.7) | 0.91 | 0.27–3.06 | 0.88 | 0.78 | 0.23–2.65 | 0.69 |
Subpleural fibrosis | 14 (35.9) | 0.94 | 0.48–1.85 | 0.87 | 0.88 | 0.45–1.73 | 0.71 |
Paravertebral fibrosis | 2 (5.1) | 1.61 | 0.36–7.08 | 0.53 | 1.56 | 0.35–6.95 | 0.56 |
Mucus plugs | 3 (7.7) | 4.12 | 1.13–14.99 | 0.03 | 4 | 1.05–15.18 | 0.04 |
Tracheal deviation | 3 (7.7) | 4.58 | 1.23–17 | 0.02 | 6.04 | 1.49–24.4 | 0.01 |
Coronary calcifications | 17 (43.6) | 1.34 | 0.7–2.56 | 0.38 | 1.39 | 0.70–2.76 | 0.35 |
Valve calcifications | 8 (20.5) | 1.38 | 0.62–3.09 | 0.43 | 1.21 | 0.53–2.77 | 0.64 |
Breast nodule | 1 (2.6) | 1.66 | 0.21–13.23 | 0.63 | 1.04 | 0.12–8.58 | 0.12 |
Categorical variables are expressed as frequency (%), while continuous variables as mean (SD). Adjustment variables in the multivariable logistic regression were age, sex and pack year. The following LDCT scan findings were not represented in this cohort: diffuse fibrosis, pulmonary trunk ectasia, pericardium pouring and thoracic cage abnormalities