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. 2022 Jan 17;12:793471. doi: 10.3389/fneur.2021.793471

Table 5.

Association between initial stroke severity and 3 months outcome by LDL-C levels and pre-ICH lipid-lowering drugs use in TSR.

OR (95% CI)
All ICH patients
(n = 4,606)
Crude Age/sex-adjusted Multivariate adjusted
3-month mortality
  <100 1.39 (0.91, 2.11) 1.35 (0.88, 2.05) 1.84 (1.28, 2.63)
  <70 1.82 (1.36, 2.42) 1.75 (1.31, 2.34) 1.33 (0.79, 2.23)
  70–99 1.13 (0.71, 1.80) 1.10 (0.69, 1.76) 1.21 (0.68, 2.14)
  100–109 0.74 (0.38, 1.45) 0.74 (0.38, 1.44) 0.71 (0.31,1.63)
  110–129 1 1 1
  130–159 0.43 (0.21, 0.88) 0.42 (0.20, 0.87) 0.38 (0.15,0.95)
  160–179 0.62 (0.21, 1.81) 0.64 (0.22, 1.89) 0.57 (0.13,2.55)
  ≥180 0.94 (0.32, 2.80) 1.04 (0.35, 3.08) 1.15 (0.32, 4.14)
  Pre-ICH lipid-lowering drugs use 0.74 (0.41, 1.34) 0.70 (0.38, 1.29) 0.84 (0.43,1.66)
3-month mRS >2
  <100 1.04 (0.90, 1.20) 0.97 (0.84, 1.13) 0.96 (0.81, 1.13)
  <70 1.02 (0.81, 1.28) 0.97 (0.77, 1.22) 0.98 (0.75, 1.29)
  70–99 1.30 (1.00, 1.68) 1.26 (0.97, 1.64) 1.27 (0.94, 1.73)
  100–109 1.26 (0.90, 1.77) 1.26 (0.89, 1.77) 1.37 (0.92, 2.04)
  110–129 1 1
  130–159 0.93 (0.69, 1.26) 0.95 (0.70, 1.29) 1
  160–179 1.12 (0.68, 1.82) 1.24 (0.76, 2.04) 1.01 (0.71, 1.44)
  ≥180 1.01 (0.57, 1.79) 1.21 (0.68, 2.16) 1.24 (0.70, 2.19)
  Pre-ICH lipid-lowering drugs use 0.94 (0.70, 1.27) 0.85 (0.63, 1.16) 1.03 (0.54, 1.97)
Initial NIHSS score >15
  <100 1.36 (1.06, 1.75) 1.35 (1.05, 1.73) 1.35 (1.13, 1.62)
  <70 1.65 (1.26, 2.16) 1.64 (1.25, 2.15) 1.53 (1.12, 2.09)
  70–99 1.34 (1.16, 1.56) 1.32 (1.14, 1.54) 1.99 (1.42, 2.79)
  100–109 1.15 (0.80, 1.64) 1.15 (0.80, 1.63) 1.20 (0.78, 1.86)
  110–129 1 1 1
  130–159 1.05 (0.75, 1.47) 1.06 (0.76, 1.48) 1.38 (0.93, 2.06)
  160–179 1.24 (0.74, 2.05) 1.26 (0.76, 1.48) 1.61 (0.86, 3.00)
  ≥180 1.02 (0.55, 1.90) 1.06 (0.57, 1.98) 1.17 (0.56, 2.46)
  Pre-ICH lipid-lowering drugs use 0.87 (0.63, 1.20) 0.85 (0.61, 1.16) 0.95 (0.65, 1.38)