Table 5.
Association between initial stroke severity and 3 months outcome by LDL-C levels and pre-ICH lipid-lowering drugs use in TSR.
OR (95% CI) | |||
---|---|---|---|
All ICH patients (n = 4,606) |
Crude | Age/sex-adjusted | Multivariate adjusted |
3-month mortality | |||
<100 | 1.39 (0.91, 2.11) | 1.35 (0.88, 2.05) | 1.84 (1.28, 2.63) |
<70 | 1.82 (1.36, 2.42) | 1.75 (1.31, 2.34) | 1.33 (0.79, 2.23) |
70–99 | 1.13 (0.71, 1.80) | 1.10 (0.69, 1.76) | 1.21 (0.68, 2.14) |
100–109 | 0.74 (0.38, 1.45) | 0.74 (0.38, 1.44) | 0.71 (0.31,1.63) |
110–129 | 1 | 1 | 1 |
130–159 | 0.43 (0.21, 0.88) | 0.42 (0.20, 0.87) | 0.38 (0.15,0.95) |
160–179 | 0.62 (0.21, 1.81) | 0.64 (0.22, 1.89) | 0.57 (0.13,2.55) |
≥180 | 0.94 (0.32, 2.80) | 1.04 (0.35, 3.08) | 1.15 (0.32, 4.14) |
Pre-ICH lipid-lowering drugs use | 0.74 (0.41, 1.34) | 0.70 (0.38, 1.29) | 0.84 (0.43,1.66) |
3-month mRS >2 | |||
<100 | 1.04 (0.90, 1.20) | 0.97 (0.84, 1.13) | 0.96 (0.81, 1.13) |
<70 | 1.02 (0.81, 1.28) | 0.97 (0.77, 1.22) | 0.98 (0.75, 1.29) |
70–99 | 1.30 (1.00, 1.68) | 1.26 (0.97, 1.64) | 1.27 (0.94, 1.73) |
100–109 | 1.26 (0.90, 1.77) | 1.26 (0.89, 1.77) | 1.37 (0.92, 2.04) |
110–129 | 1 | 1 | |
130–159 | 0.93 (0.69, 1.26) | 0.95 (0.70, 1.29) | 1 |
160–179 | 1.12 (0.68, 1.82) | 1.24 (0.76, 2.04) | 1.01 (0.71, 1.44) |
≥180 | 1.01 (0.57, 1.79) | 1.21 (0.68, 2.16) | 1.24 (0.70, 2.19) |
Pre-ICH lipid-lowering drugs use | 0.94 (0.70, 1.27) | 0.85 (0.63, 1.16) | 1.03 (0.54, 1.97) |
Initial NIHSS score >15 | |||
<100 | 1.36 (1.06, 1.75) | 1.35 (1.05, 1.73) | 1.35 (1.13, 1.62) |
<70 | 1.65 (1.26, 2.16) | 1.64 (1.25, 2.15) | 1.53 (1.12, 2.09) |
70–99 | 1.34 (1.16, 1.56) | 1.32 (1.14, 1.54) | 1.99 (1.42, 2.79) |
100–109 | 1.15 (0.80, 1.64) | 1.15 (0.80, 1.63) | 1.20 (0.78, 1.86) |
110–129 | 1 | 1 | 1 |
130–159 | 1.05 (0.75, 1.47) | 1.06 (0.76, 1.48) | 1.38 (0.93, 2.06) |
160–179 | 1.24 (0.74, 2.05) | 1.26 (0.76, 1.48) | 1.61 (0.86, 3.00) |
≥180 | 1.02 (0.55, 1.90) | 1.06 (0.57, 1.98) | 1.17 (0.56, 2.46) |
Pre-ICH lipid-lowering drugs use | 0.87 (0.63, 1.20) | 0.85 (0.61, 1.16) | 0.95 (0.65, 1.38) |