Figure 1.

Rate of postacute sequelae of SARS-CoV-2 infection, by RNAemia and worst clinical severity. Overall, 83.3% (25/30) of initially RNAemic patients had 1 or more postacute symptoms at follow-up, compared with 41.2% (40/97) of non-RNAemic patients (difference, 42.1%; 95% CI, 23.4%–60.8%; P = .0001322). Conditional on worst severity within 30 days of enrollment (mild = discharged from ED [n = 23]; moderate = hospitalized, requiring no more than oxygen by nasal cannula [n = 80]; severe = hospitalized, requiring high-flow nasal cannula or mechanical ventilation [n = 21]), RNAemia on presentation was associated with significantly higher rates of PASC for moderate severity (difference, 36.8%; 95% CI, 9.5%–64.0%; P = .01544). ^∗P < .05. Abbreviations: COVID-19, coronavirus disease 2019; ED, emergency department; PASC, postacute sequelae of COVID-19; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.