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. 2022 Jan 17;8:780089. doi: 10.3389/fmolb.2021.780089

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Copyright © 2022 Han, Lei, Chen, Zhang, Huang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IGF2BP2 regulates MALTA1 expression in NSCLC. (A,B) Real-time quantitative PCR analysis IGF2BP2 regulates the expression of MALAT1. (C,D) MALAT1 half-life determination. (E) RIP-PCR analysis of the interaction between IGF2BP2 and MALAT1. (F) mRIP-PCR analysis of m6A modification of MALAT1. (G–J) CCK-8 and clone formation experiments analyze the effect of MALAT1 on the proliferation of non-small cell lung cancer cell lines. Data are presented as mean ± SD. p values are calculated by unpaired two-sided t-test.