Table 1.
Participant clinical and pathologic characteristics at baseline actigraphy visit (N = 167)a
| Characteristic | Value |
|---|---|
| Age, yr | 85.9 (5.8) |
| Education, yr | 14.6 (2.6) |
| Sex (%, n; female) | 66.5% (111) |
| MMSE (median, IQR) | 27 (25, 29) |
| Average physical activity (daily counts) | 2.10 (1.15) |
| Actigraphy visits (%, n) | 1.05 (1.2) range: 0-6 |
| 1 | 100% (167) |
| 2 | 64.1% (107) |
| 3 | 34.7% (58) |
| 4 | 18.6% (31) |
| 5 | 10.8% (18) |
| 6 | 1.8% (3) |
| Neurocognitive diagnosis (%, n) | |
| Clinically normal | 39.5% (66) |
| Mild cognitive impairment | 27.5% (46) |
| Dementia | 32.9% (55) |
| Years to death | 3.2 (1.6) |
| Postmortem interval, h (median, IQR) | 6.3 (5.2, 8.3) |
| Pathologic AD (Reagan criteria, %, n) | 59.9% (100) |
| Proportion activated microglia | |
| Inferior temporal gyrus | 0.08 (0.06) |
| Middle frontal gyrus | 0.09 (0.06) |
| VM caudate | 0.06 (0.05) |
| Posterior putamen | 0.09 (0.05) |
a>Data are mean and SD. MMSE, Mini Mental Status Examination; IQR, interquartile range. Daily physical activity counts divided by 1 × 105 (∼1 SD) to facilitate presentation.