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. 2021 Oct 14;118(2):542–555. doi: 10.1093/cvr/cvab322

Figure 5.

Figure 5

Top regulated Gene Ontology (GO) terms are linked to cardiomyocytes and immune response. For each GO term, the gene ratio of regulated genes and annotated genes was calculated. Displayed are GO terms with a gene ratio >0.2 and a q-value <0.001. Whether the majority of genes in this term is up- or downregulated is indicated on the X-axis (z score). The q-value of the respective GO term is displayed by the colour gradient of the respective dot. The size of the dots represents the number of annotated genes. The GO terms are linked to immune response (green) or cardiomyocyte structure (purple). However, cardiomyocyte-specific GO terms are downregulated (negative z score), while GO terms linked to immune response are upregulated (positive z score).