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. 2022 Jan 10;9:755254. doi: 10.3389/fcell.2021.755254

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Copyright © 2022 Tan, Hu, Ming, Lv, Yan, Peng, Bai, Xiao, Zhang, Tang, Wang and Tan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-409-3p decrease the cell toxicity of ATXN3-Q78-GFP (A) the aggregates of ATXN3-Q78-GFP were observed in SH-SY5Y cells with transfection of miR-409-3p mimic or negative control (NC). (B) Statistical results of apoptosis detected by flow cytometry in SH-SY5Y cells with transfection of miR-409-3p mimic or negative control (NC). Student t-test, *, p < 0.05. (C) Apoptosis were detected by flow cytometry in SH-SY5Y cells with transfection of miR-409-3p mimic or negative control (NC) using annexin-V-FITC and PI staining.