TABLE 2.
Ferroptosis-related genes with survival significance in the univariate Cox regression analysis of the TCGA-LAML cohort.
| Gene name | HR | HR.95L | HR.95H | p-value |
|---|---|---|---|---|
| G6PD | 1.042662659 | 1.021730497 | 1.064023657 | 5.40E-05 |
| GPX4 | 1.029261441 | 1.01470048 | 1.044031353 | 7.26E-05 |
| LPCAT3 | 1.26784648 | 1.126151189 | 1.427370244 | 8.68E-05 |
| AIFM2 | 2.35902572 | 1.522954065 | 3.654084172 | 0.000121029 |
| ACSF2 | 1.416086083 | 1.183993793 | 1.693674245 | 0.000139401 |
| SLC1A5 | 1.034660853 | 1.007310121 | 1.062754218 | 0.012673093 |
| GSS | 1.084599685 | 1.017485242 | 1.15614107 | 0.012708482 |
| HSPB1 | 1.021101123 | 1.004464707 | 1.038013079 | 0.012721046 |
| FTH1 | 1.004820236 | 1.001006148 | 1.008648857 | 0.013203117 |
| FADS2 | 1.044215109 | 1.008006196 | 1.081724694 | 0.01626862 |
| DPP4 | 1.315339205 | 1.044859818 | 1.655836691 | 0.01961824 |
| KEAP1 | 1.042701327 | 1.006702842 | 1.079987074 | 0.019667367 |
| PGD | 1.011288392 | 1.001788789 | 1.020878077 | 0.019747746 |
| CS | 1.073417219 | 1.010825563 | 1.139884634 | 0.020820444 |
| GOT1 | 1.182375661 | 1.02398682 | 1.365263865 | 0.022430936 |
| SQLE | 1.106383386 | 1.013803784 | 1.207417269 | 0.023363045 |
| CHAC1 | 1.533037962 | 1.053292623 | 2.231293889 | 0.025674875 |
| CISD1 | 1.33620604 | 1.026729735 | 1.738964521 | 0.031067487 |
| RPL8 | 1.00324892 | 1.000260989 | 1.006245776 | 0.033052858 |
| NCOA4 | 0.992630046 | 0.98539641 | 0.999916784 | 0.047449628 |
TCGA, The Cancer Genome Atlas; AML, acute myeloid leukemia; HR, hazard ratio.