Figure 1.

RNA sequencing analysis of healthy and idiopathic pulmonary fibrosis (IPF) fibroblasts (FBs). (A) Volcano plot and (B) heatmap of differentially expressed genes (DEGs) in healthy and IPF FBs by RNA sequencing. Cutoff FDR was <0.05 and fold change >1.5. (C) Annotation of differentially expressed genes in healthy and IPF FBs using DAVID. BP = biological process; DAVID = database for annotation, visualization and integrated discovery; ECM = extracellular matrix; FDR = false discovery rate; KEGG = Kyoto Encyclopedia of Genes and Genomes.