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Experimental design. A schematic of hemizygous breeding strategies and serial MEx treatment in the Hmox1−/− model system of experimental preeclampsia is shown. E = Embryonic Day; F = female; IV = intravenous; KO = Knockout; Hmox1−/− = heme oxygenase-1–null mouse; M = male; MEx = mesenchymal stromal cell derived extracellular vesicles; PE = preeclampsia; PN = Postnatal Day; WT = wild-type.
