Table 2.
The ulcer protective effect of the A. perryi flower extract (APFE) on the pylorus ligation-induced ulcer model.
| Treatment | Dose | Parameters | ||||
|---|---|---|---|---|---|---|
| Gastric volume (ml) | pH | Total acidity (mEq/l) | Free acidity (mEq/l) | Ulcer index | ||
| Control | 1 ml/kg | 8.47 ± 0.15 | 3.21 ± 0.13 | 120.83 ± 2.20 | 94.32 ± 0.31 | 3.58 ± 0.09 |
| APFE | 250 mg/kg | 3.62 ± 0.21^ | 5.52 ± 0.11∗ | 93.17 ± 1.30∗ | 84.00 ± 1.18∗ | 1.69 ± 0.03∗ |
| 500 mg/kg | 2.32 ± 0.12∗ | 6.73 ± 0.12∗ | 65.33 ± 1.38∗ | 48.67 ± 2.59∗ | 1.01 ± 0.03 | |
| Ranitidine | 50 mg/kg | 4.25 ± 0.21∗ | 5.35 ± 0.15∗ | 37.0 ± 0.17∗ | 17.0 ± 0.24∗ | 1.00 ± 0.03∗ |
Control: rats received only distilled water; APFE: rats received the Aloe perryi flower extract in a dose level (250 and 500 mg/kg) (p.o.); ranitidine: rats received ranitidine which is dissolved in distilled water and given in a dose level (50 mg/kg) (p.o.) and served as a standard drug. n = 6/group. Values are expressed as mean ± SEM (n = 6). ∗P value is <0.001 and ^P value is <0.05 versus control.