Table 4.
Distribution of the levels of the three types of microRNAs by subgroups.
| miR-9-5p | miR-17-5p | miR-148a-3p | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | P1 | P2 | Cases | Controls | P1 | P2 | Cases | Controls | P1 | P2 | |
| Menopause status | ||||||||||||
| Premenopause | 0.395 ± 0.312 | 0.356 ± 0.233 | 0.587 | 0.502 | 2.138 ± 0.716 | 2.177 ± 0.608 | 0.844 | 0.110 | 2.410 ± 0.784 | 2.086 ± 0.552 | 0.092 | 0.149 |
| Postmenopause | 0.557 ± 0.326 | 0.001 | 2.045 ± 0.551 | 0.307 | 2.609 ± 0.931 | 0.002 | ||||||
| ER status | ||||||||||||
| + | 0.492 ± 0.329 | 0.356 ± 0.233 | 0.035 | 0.895 | 2.156 ± 0.621 | 2.177 ± 0.608 | 0.883 | 0.282 | 2.645 ± 0.810 | 2.086 ± 0.552 | <0.001 | 0.121 |
| - | 0.549 ± 0.330 | 0.008 | 1.933 ± 0.533 | 0.130 | 2.417 ± 1.014 | 0.089 | ||||||
| PR status | ||||||||||||
| + | 0.484 ± 0.325 | 0.356 ± 0.233 | 0.049 | 0.944 | 2.026 ± 0.605 | 2.177 ± 0.608 | 0.297 | 0.380 | 2.482 ± 0.955 | 2.086 ± 0.552 | 0.024 | 0.224 |
| - | 0.563 ± 0.320 | 0.002 | 2.128 ± 0.587 | 0.756 | 2.656 ± 0.810 | 0.001 | ||||||
| HER2 status | ||||||||||||
| + | 0.577 ± 0.357 | 0.356 ± 0.233 | 0.001 | 0.049 | 2.118 ± 0.591 | 2.177 ± 0.608 | 0.659 | 0.797 | 2.570 ± 0.863 | 2.086 ± 0.552 | 0.002 | 0.481 |
| - | 0.357 ± 0.251 | 0.985 | 1.949 ± 0.603 | 0.093 | 2.524 ± 0.992 | 0.035 | ||||||
Abbreviations: ER: estrogen receptor; HER2: human epidermal growth factor receptor 2; PR: progesterone receptor; P1: P value compared with controls; P2: P value compared among subgroups of cases.