Table 1. Baseline clinical characteristics.
| Characteristics | Before PS match | p value | After PS match | p value | ||
|---|---|---|---|---|---|---|
| TyG＜8.33 ( n : 829) |
TyG ≥ 8.33 ( n : 826) |
TyG＜8.33 ( n : 505) |
TyG ≥ 8.33 ( n : 505) |
|||
| TyG index | 8.0±0.2 | 8.8±0.7 | ＜0.001 | 8.0±0.2 | 8.7±0.4 | ＜0.001 |
| Age, years | 67.4±10.2 | 63.9±10.2 | ＜0.001 | 65.6±10.5 | 65.9±9.7 | 0.674 |
| Male gender | 604 (73.1) | 619 (74.7) | 0.474 | 364 (72.1) | 371 (73.5) | 0.621 |
| BMI, kg/m 2 | 24.8±3.6 | 26.0±3.2 | ＜0.001 | 25.5±3.6 | 25.6±3.1 | 0.720 |
| SBP, mmHg | 129.2±17.7 | 127.1±17.8 | 0.013 | 128.2±17.6 | 127.6±17.7 | 0.599 |
| DBP, mmHg | 74.5±11.5 | 74.6±11.2 | 0.769 | 74.7±11.7 | 74.3±10.5 | 0.550 |
| Heart rate, bpm | 68.9±12.8 | 68.8±11.5 | 0.901 | 68.1±12.3 | 68.8±11.3 | 0.398 |
| Medical history | ||||||
| Current/ex-Smoker | 445 (53.9) | 491 (59.2) | 0.028 | 276 (54.7) | 286 (56.6) | 0.526 |
| Hypertension | 586 (70.9) | 615 (74.2) | 0.139 | 357 (70.7) | 37.6 (74.5) | 0.180 |
| Stroke | 194 (23.5) | 148 (17.9) | 0.005 | 97 (19.2) | 107 (21.2) | 0.433 |
| OMI | 119 (14.4) | 111 (13.4) | 0.550 | 75 (14.9) | 70 (13.9) | 0.654 |
| Previous PCI/CABG | 298 (36.1) | 295 (35.6) | 0.835 | 199 (39.4) | 171 (33.9) | 0.067 |
| MetS | 148 (17.9) | 378 (45.8) | ＜0.001 | 107 (21.2) | 177 (35.0) | ＜0.001 |
| Medication used before admission | ||||||
| Antiplatelet agent | 518 (62.7) | 521 (62.8) | 0.955 | 330 (65.3) | 304 (60.2) | 0.091 |
| ACEI/ARB | 299 (36.2) | 329 (39.7) | 0.144 | 183 (36.2) | 204 (40.4) | 0.174 |
| Beta-blocker | 213 (25.8) | 275 (33.2) | 0.001 | 149 (29.5) | 138 (27.3) | 0.443 |
| CCB | 297 (36.0) | 314 (37.9) | 0.418 | 184 (36.4) | 189 (37.4) | 0.744 |
| Diuretics | 42 (5.1) | 57 (6.9) | 0.124 | 25 (5.0) | 26 (5.1) | 0.886 |
| Statins | 348 (42.1) | 397 (47.9) | 0.019 | 233 (46.1) | 224 (44.4) | 0.569 |
| Laboratory values | ||||||
| WBC, 10 9 /L | 6.4±2.0 | 6.9±2.3 | ＜0.001 | 6.4±1.9 | 6.6±2.2 | 0.215 |
| Neutrophil ratio, % | 66.6±9.0 | 65.8±9.0 | 0.065 | 66.3±8.9 | 66.1±9.3 | 0.775 |
| Hemoglobin, g/L | 134.2±15.1 | 137.6±15.6 | ＜0.001 | 135.9±15.1 | 135.8±15.7 | 0.912 |
| FPG, mmol/L | 4.8±0.6 | 5.4±0.9 | ＜0.001 | 4.8±0.5 | 5.4±0.9 | ＜0.001 |
| HbA1c, % | 5.7±0.4 | 5.8±0.5 | ＜0.001 | 5.7±0.5 | 5.6±0.6 | 0.538 |
| Albumin, g/L | 39.9±3.6 | 40.7±3.7 | ＜0.001 | 40.4±3.5 | 40.4±3.9 | 0.926 |
| Creatinine, umol/L | 74.1 (65.2, 86.0) | 76.0 (66.0, 88.6) | 0.038 | 74.2 (64.9, 86.0) | 75.3 (66.0, 88.0) | 0.176 |
| eGFR, ml/min/1.73 m 2 | 84.8 (70.9, 98.2) | 85.3 (71.5, 98.2) | 0.664 | 85.5 (72.5, 99.9) | 83.3 (70.5, 96.0) | 0.077 |
| TC, mmol/L | 3.1±0.4 | 3.1±0.4 | 0.102 | 3.1±0.4 | 3.1±0.4 | 0.611 |
| TG, mmol/L | 0.8±0.2 | 1.6±0.7 | ＜0.001 | 0.8±0.2 | 1.4±0.4 | ＜0.001 |
| LDL-C, mmol/L | 1.5±0.1 | 1.6±0.2 | ＜0.001 | 1.5±0.2 | 1.5±0.2 | 0.311 |
| HDL-C, mmol/L | 1.2±0.3 | 1.0±0.3 | ＜0.001 | 1.1±0.3 | 1.1±0.2 | 0.878 |
| Echocardiography | ||||||
| LVEF, % | 63.9±9.7 | 64.6±8.4 | 0.094 | 63.9±9.4 | 64.3±8.7 | 0.554 |
| Angiography findings | ||||||
| Multi-vessel/LM | 665 (80.5) | 683 (82.4) | 0.325 | 279 (55.2) | 287 (56.8) | 0.612 |
| Proximal LAD | 382 (46.2) | 399 (48.1) | 0.443 | 230 (45.5) | 249 (49.3) | 0.231 |
| In-hospital treatment | ||||||
| PCI/CABG | 461 (55.8) | 484 (58.4) | 0.290 | 279 (55.2) | 287 (56.8) | 0.612 |
| Antiplatelet agent | 794 (96.1) | 800 (96.5) | 0.685 | 485 (96.0) | 489 (96.8) | 0.497 |
| ACEI/ARB | 415 (50.2) | 418 (50.4) | 0.942 | 250 (49.5) | 253 (50.1) | 0.850 |
| Beta-blocker | 534 (64.6) | 579 (69.8) | 0.024 | 347 (68.7) | 336 (66.5) | 0.459 |
| CCB | 297 (36.0) | 316 (38.1) | 0.363 | 184 (36.4) | 191 (37.8) | 0.648 |
| Diuretics | 72 (8.7) | 71 (8.6) | 0.912 | 39 (7.7) | 41 (8.1) | 0.816 |
| Statins | 742 (89.8) | 754 (91.0) | 0.438 | 454 (89.9) | 458 (90.7) | 0.671 |
| Hospital stay, day | 5 (4, 7) | 5 (4, 7) | 0.778 | 5 (4, 7) | 6 (4, 7) | 0.938 |
Dates are presented as mean±SD, median (IQR) or number (%).
TyG, triglyceride-glucose index; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; OMI, old myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; MetS, metabolic syndrome; ACEI/ARB, angiotensin-converting enzyme inhibitor/ angiotensin receptor blocker; CCB; calcium channel blocker; WBC, white blood cell; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; eGFR, estimated glomerular filtration rate; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; LM, left main coronary artery; LAD, left anterior descending.