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. 2022 Jan 18;13:754814. doi: 10.3389/fnsyn.2021.754814

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Copyright © 2022 Sneve and Piatkevich.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FingRs and related tools. (A) Schematic diagram of FingRs for post-synaptic labeling of excitatory and inhibitory synapses, using endogenous PSD-95 and gephyrin, respectively. (B) Schematic diagram of CAMPARI2, a genetically encoded calcium indicator, which changes fluorescent wavelength in response to combined blue light and high calcium ion levels. CAMPARI2 forms the fluorescent component of SynTagMA. (C) Schematic diagram of pre-SynTagMA, which marks synaptophysin, and post-SynTagMA, which marks endogenous PSD-95 with the aid of a PSD-95-specific FingR. Created with Biorender.com.