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. 2022 Jan 31;12:1672. doi: 10.1038/s41598-022-05658-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Chronic inflammation markers and association with RLS. Visualisation of the results from the logistic regression models using CRP levels (top row), CRP as a binary variable (middle row), and suPAR levels (bottom row) as the independent variable and RLS status (left column) or RLS with frequent symptoms (right column) as the dependent variable, using three different models. Model 0 = Crude association. Model 1 = adjusting for sex and age. Model 2 = adjusting for sex, age, smoking status and BMI. Data are presented as odds ratios (OR) with 95% confidence intervals, and an asterisk (*) denotes a P value < 0.05. OR = odds ratio. High CRP is classified as having CRP levels above 3 mg/L but below 10 mg/L.