Table 1.
Demographic descriptive statistics of RLS cases and controls in the DBDS cohort with available CRP data (N = 3564) and the DBDS cohort with available suPAR data (N = 2546).
| DBDS cohort with CRP and RLS data (N = 3564) | DBDS cohort with suPAR and RLS data (N = 2546) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Controls N = 3394 | RLS cases N = 170 (4.8%) | P valuea | Controls N = 2420 | RLS cases N = 126 (4.9%) | P valuea | |||||
| N | % | N | % | N | % | N | % | |||
| Sex | ||||||||||
| Male | 1978 | 58.3 | 76 | 44.7 | < 0.001 | 1415 | 58.5 | 57 | 45.2 | 0.003 |
| Female | 1416 | 41.7 | 94 | 55.3 | 1005 | 41.5 | 69 | 54.8 | ||
| Age | ||||||||||
| Years median (IQR) | 38.9 (29.4–47.3) | 40.5 (31.6–48.4) | 0.245 | 39.1 (29.8–47.3) | 40.4 (32.4–48.2) | 0.312 | ||||
| BMI | ||||||||||
| Median (IQR) | 25.1 (23.0–27.7) | 25.2 (22.5–28.1) | 0.627 | 25.1 (23.1–27.7) | 25.2 (22.2–28.3) | 0.614 | ||||
| < 18.5 | 16 | 0.5 | 0 | 0 | 0.844 | 15 | 0.6 | 0 | 0 | 0.933 |
| 18.5–25 | 1653 | 48.7 | 82 | 48.2 | 1170 | 48.3 | 62 | 49.2 | ||
| 25–30 | 1304 | 38.4 | 68 | 40.0 | 933 | 38.6 | 46 | 36.5 | ||
| 30–35 | 316 | 9.3 | 14 | 8.2 | 223 | 9.2 | 13 | 10.3 | ||
| 35–40 | 85 | 2.5 | < 5 | < 2.9 | 66 | 2.7 | < 5 | < 4 | ||
| > 40 | 20 | 0.6 | < 5 | < 2.9 | 13 | 0.5 | < 5 | < 4 | ||
| Smoking status | ||||||||||
| Non-smoker | 3008 | 88.6 | 149 | 87.6 | 0.470 | 2160 | 89.3 | 107 | 84.9 | 0.170 |
| < 1 cigarette per day | 118 | 3.5 | < 5 | < 2.9 | 82 | 3.4 | < 5 | < 4 | ||
| > 1 cigarette per day | 268 | 7.9 | 17 | 10 | 178 | 7.4 | 15 | 11.9 | ||
| Duration between donation date for hsCRP/suPAR measurement and RLS questionnaire completion | ||||||||||
| Years, median (IQR) | 6.2 (5.6–7.0) | 6.2 (5.7–7.0) | 0.611 | 6.3 (5.7–7.0) | 6.2 (5.7–7.0) | 0.786 | ||||
DBDS danish blood donor study cohort, IQR interquartile range.
aFor comparison of the two groups, chi-square test was used for categorical variables and Kruskal–Wallis rank test was used for continuous variables.
Significant values are in [bold].