Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 31;12:1659. doi: 10.1038/s41598-022-05660-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Activin A is highly expressed in tumor specimens and tumor-derived cell lines of genetically engineered mouse models of PDAC. (A) Immunofluorescence images of activin A (AF488) in normal mouse pancreas tissue and tumor specimens of KPC 8060 and KPC 8069 mice. Scale bar = 50 µm. (B) Measurement of serum activin A levels in healthy control C567BL/6 J and KPC mice. (C) Immunoblotting analysis of activin A expression in healthy control C57BL/6 J mouse pancreas tissue and KPC8069 cell lysates. (D) Relative Inhba mRNA expression levels in healthy control C57BL/6 J mouse pancreas tissue and KPC8069 cells. (E) Measurement of activin A concentration in CM from KPC8060 and KCP8069 cells along with RPMI-1640. (F) Measurement of activin A concentration in CM from KPC8069 cells at 60% confluency, 100% confluency and 100% confluency following reintroduction (a blue bar) of fresh culture medium.