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. 2022 Jan 31;12(1):21. doi: 10.1038/s41408-022-00611-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a PFS (months) and b OS (years) in MM patients with no HR factors (stage I) (red curve), 1 HR factor (stage II) (green curve), and ≥2 HR factors (stage III) (blue curve). HR factors are defined as any of: HR IgH translocations, 1q gain/amplification, chromosome 17 abnormality [(del)17p/monosomy 17], ISS stage III, and LDH > ULN. del: deletion, HR: high-risk, IgH immunoglobulin heavy chain gene locus, ISS international staging system, LDH lactate dehydrogenase, MASS Mayo Additive Staging System, MM multiple myeloma, OS overall survival, PFS progression-free survival, ULN upper limit of normal. The P values for each pair of groups are presented between the corresponding curves.