Table 2.
Cytogenetic abnormalities in multiple myeloma patients.
| Primary abnormalities | Tested N | Abnormality N (%) |
|---|---|---|
| IgH translocations | ||
| t(4;14) | 2519 | 248 (10) |
| t(14;16) | 2517 | 99 (4) |
| t(11;14) | 2522 | 519 (21) |
| Trisomies | 2491 | 1374 (55) |
| Secondary abnormalities | ||
| 1q gain/amplification | 1896 | 585 (31) |
| Chromosome 17 abnormality (17pdel/monosomy 17) | 2499 | 337 (13) |
| Monosomy 13 | 2513 | 926 (37) |
| MYC rearrangement | 1856 | 160 (9) |
Prevalence of recurrent primary and secondary cytogenetic abnormalities in patients tested by FISH at diagnosis.
IgH immunoglobulin heavy chain gene locus, del deletion.