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. 2022 Jan 31;13:578. doi: 10.1038/s41467-022-28138-6

Fig. 3. Distinct Fpr2 expression in livers of female mice.

Fig. 3

a qRT-PCR for hepatic formyl peptide receptor 2 (Fpr2) from WT male and female mice fed chow or CDAHFD. Data represent the mean ± S.E.M. (n ≥ 4/group, *p < 0.05, **p < 0.005 vs own control). b Representative Fpr2-immunostained liver images from these mice. Magnified images of Chow-WT female in right panel are shown at X100 (Scale bar, 50 μm). c Quantitative Fpr2-stained data from these mice. The numbers of Fpr2-positive hepatocytic cells were counted per filed and divided by the number of total hepatocytes per field. Data represent the mean ± S.E.M. (n ≥ 4/group, *p < 0.05, **p < 0.005 vs own control). d Amount of serum estradiol in these mice. Data represent the mean ± S.E.M. (n ≥ 4/group, *p < 0.05, **p < 0.005 vs own control). e Pearson’s correlation between serum estradiol and Fpr2 expression of Chow-WT female mice (n = 4/group, r = 0.883, p < 0.001). Gray circles represent individual data points. See Supplementary Data for statistical details.