Table 1.
Baseline characteristics of matched HSV and control cohorts
| HSV subjects (n = 87,687) | Controls (n = 217,895) | SMD | |
|---|---|---|---|
| Sex | |||
| Female | 5794 (6.6%) | 11,863 (5.4%) | 4.9 |
| Male | 81,893 (93.4%) | 206,032 (94.6%) | 4.9 |
| Race | |||
| (Missing) | 2944 (3.4%) | 7438 (3.4%) | 0.3 |
| Black | 16,513 (18.8%) | 40,623 (18.6%) | 0.5 |
| Other | 3988 (4.5%) | 8571 (3.9%) | 3.0 |
| White | 64,242 (73.3%) | 161,263 (74.0%) | 1.7 |
| Age | |||
| 50–59 | 37,693 (43.0%) | 92,043 (42.2%) | 1.5 |
| 60–69 | 32,152 (36.7%) | 81,170 (37.3%) | 1.2 |
| 70–79 | 12,911 (14.7%) | 32,838 (15.1%) | 1.0 |
| 80 + | 4931 (5.6%) | 11,844 (5.4%) | 0.8 |
| Rurality | |||
| (Missing) | 133 (0.2%) | 305 (0.1%) | 0.3 |
| Rural and highly rural | 28,196 (32.2%) | 79,047 (36.3%) | 8.7 |
| Urban | 59,358 (67.7%) | 138,543 (63.6%) | 8.7 |
| Priority | |||
| (Missing) | 16 (0.0%) | 39 (0.0%) | 0.0 |
| Level 1 | 11,694 (13.3%) | 27,793 (12.8%) | 1.7 |
| Level 2 | 5309 (6.1%) | 13,128 (6.0%) | 0.1 |
| Level 3 | 9981 (11.4%) | 25,139 (11.5%) | 0.5 |
| Level 4 | 242 (0.3%) | 484 (0.2%) | 1.1 |
| Level 5 | 23,983 (27.4%) | 59,044 (27.1%) | 0.6 |
| Level 6 | 5317 (6.1%) | 13,347 (6.1%) | 0.3 |
| Level 7 | 7066 (8.1%) | 17,694 (8.1%) | 0.2 |
| Level 8 | 24,079 (27.5%) | 61,227 (28.1%) | 1.4 |
| Comorbidities | |||
| PTSD | 10,907 (12.4%) | 25,465 (11.7%) | 2.3 |
| TBI | 108 (0.1%) | 323 (0.1%) | 0.7 |
| Ischemic stroke | 1628 (1.9%) | 5856 (2.7%) | 5.6 |
| Stroke TIA | 2255 (2.6%) | 7460 (3.4%) | 5.0 |
| Diabetes | 18,497 (21.1%) | 60,118 (27.6%) | 15.2 |
| Addiction disorder | 14,495 (16.5%) | 43,358 (19.9%) | 8.7 |
| Anxiety | 7873 (9.0%) | 17,391 (8.0%) | 3.6 |
| Depressive disorder | 15,349 (17.5%) | 36,198 (16.6%) | 2.4 |
| CHF | 3213 (3.7%) | 11,027 (5.1%) | 6.8 |
| Schizophrenia | 1738 (2.0%) | 7848 (3.6%) | 9.8 |
| COPD | 7295 (8.3%) | 22,389 (10.3%) | 6.7 |
| Autoimmune disease | 1460 (1.7%) | 2975 (1.4%) | 2.5 |
| Alcohol use disorder | 4276 (4.9%) | 13,247 (6.1%) | 5.3 |
| Care assessment needs score—average 1-year probability | |||
| Mortality | 3% | 3% | 6.5 |
| Hospitalization | 16% | 14% | 11.0 |
| Any visit | 17% | 15% | 9.2 |