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. 2022 Feb 1;48(3):322–331. doi: 10.1007/s00134-021-06615-8

Table 2.

Mental health outcomes and quality of life in family members

T0, N = 166 T1, N = 153 T2, N = 166 Difference (95% CI) T0 vs. T2 p value
HADS-anxiety,a Median [IQR] 3 [1–6] 5 [2–8] 4.5 [2–8] 1 [0.5 to 1.5]  < 0.001
HADS-depression,a Median [IQR] 1 [0–5] 3 [0.5–8] 3 [0–7] 1 [0.5 to 1.5]  < 0.001
IES-6,b Median [IQR] N.A 0.8 [0.3–2] 1 [0.3–1.5] N.A N.A
SF-12 PCS,c Mean (SD) 54.2 (8.9) 51.3 (11.2) 51.9 (10.9) − 2.4 (0.8 to − 4) 0.004
SF-12 MCS,c Mean (SD) 51.6 (8.9) 41.3 (12.9) 46.1 (11) − 5.5 (− 7.4 to − 3.6) < 0.001

Differences in HADS and IES-6 scores are presented as median differences and SF-12 scores as mean differences. Differences are based on complete cases

SD standard deviation, IQR interquartile range, CI confidence interval, T0 baseline measurement, T1 3-month follow-up, T2 12-month follow-up

aHospital Anxiety and Depression scale

bImpact of events scale-6

c12-item Short Form Health Survey, physical and mental component score (PCS and MSC, respectively)