Effect of the 5-week CUS protocol and co-treatments on serum levels of (a) IL-1β and (b) IL-18. Data is expressed as the mean of 7 − 8 experiments ± SEM, using one-way ANOVA with Tukey−Kramer multiple comparison post-test; as compared to normal (*), CUS (@), Escita (&), and Dapa ($)-treated groups (p ˂ 0.05). B BQ-788, CUS chronic unpredictable stress, Dapa dapagliflozin, Escita escitalopram, IL interleukin