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Effect of the 5-week CUS protocol and co-treatments on hippocampal (a) ET-1 contents, (b) miR-125a-5p, and (c) ETR gene expressions. Data is expressed as the mean of 6 − 8 experiments ± SEM, using one-way ANOVA with Tukey−Kramer multiple comparison post-test; as compared to normal (*), CUS (@), Escita (&), and Dapa ($)-treated groups (p ˂ 0.05). B BQ-788, CUS chronic unpredictable stress, Dapa dapagliflozin, Escita escitalopram, ET-1 endothelin-1, ETRs endothelin receptors
