Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Imputation concordance for F508del using TOPMed and reduced CFGP reference panels. The true R2 for TOPMed and reduced CFGP imputed results are 0.835 and 0.926, and the sum of squared error for TOPMed and reduced CFGP are 117.58 and 82.42, respectively. The main reason that TOPMed is slightly worse is that it tends to underestimate the deletion frequency.
