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. 2022 Jan 11;3(2):100090. doi: 10.1016/j.xhgg.2022.100090

Figure 2.

Figure 2

Histograms of differences between reduced CFGP true R2 and TOPMed true R2 to compare the imputation quality of the two reference panels. (A) For overall chr7. Almost all variants are located to the left half, which means TOPMed is predominantly better than the reduced CFGP reference panel. (B) For CFTR region only. The advantage of TOPMed reference panel over the reduced CFGP becomes less pronounced.