Fig. 3.

– A - Representative recordings of H₂O₂ concentration dynamics obtained in vivo in the striatum (blue-green) and in a 0.2% agarose block at 37 °C (grey). Circles represent experimental data while lines correspond to the theoretical trace obtained by modelling expression (1). B – Experimental design used, comprising a micropipette filled with a 1 mM H₂O₂ solution coupled to a CFM-RP-Nafion® sensor for H₂O₂ detection. Interval of distance (d) between source and detector as well as for the volume and radius of applied H₂O₂ bolus are discriminated. As drawn, d = 300 μm and r = 100 μm. C – Effective diffusion coefficient values calculated by modelling experimental data with Eq. (1). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)