Table 1.

Comparison of decay time constant (k) and half-life (t_1/2) of H₂O₂ signals obtained in response to puff ejections of a 1 mM H₂O₂ solution, unless otherwise indicated. Data were obtained in ex vivo acute striatal slices and 0.2% agarose slices, and in vivo in the dorsal medial striatum in anesthetized rat and in a 0.2% agarose block at 37 °C. Values represent mean ± SEM. *p < 0.0001 as compared to control slices and #p < 0.001 as compared to in vivo control (1 mM H₂O₂).

Experimental Model (N)		k / s−1	t1/2 / s
Ex vivo- Striatum Slices	Control (44)	0.32 ± 0.02	2.5 ± 0.1
	MC (5)	0.12 ± 0.01*	5.8 ± 0.5*
	Agarose 0.2% (5)	0.11 ± 0.01*	6.5 ± 0.3*
In vivo- Dorsal Medial Striatum	Control (121)	0.34 ± 0.01	2.2 ± 0.1
	10 mM H2O2 (42)	0.23 ± 0.02#	3.5 ± 0.2#
	A.D. (19)	0.21 ± 0.03#	4.8 ± 0.7#
	Agarose 0.2% (26)	0.04 ± 0.004#	18.6 ± 1.2#

MC – metabolically compromised slices, perfused with 0 mM glucose, 10 mM saccharose and 10 mM CN⁻.

A.D. – after death evoked by lethal dose of pentobarbital.