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. 2022 Jan 18;11:783335. doi: 10.3389/fonc.2021.783335

Table 2.

Comparison of baseline characters of 122 patients with high risk of recurrence concerning PD-L1 level.

PD-L1 (−) PD-L1 (+) p
N = 79 N = 43
Age 52.6 + 12.2 52.2 + 12.2 0.857
Age ≥55 (%) 31 (39.2) 17 (39.5) 1.000
Male (%) 74 (93.7) 38 (88.4) 0.321
Max tumor size 7.1 + 2.9 7.5 + 4.2 0.500
Size ≥5 cm (%) 63 (79.7) 31 (72.1) 0.372
Multiple tumors (%) 20 (25.3) 17 (39.5) 0.148
Vascular invasion (VI)
Macro-VI (%) 16 (20.3) 13 (30.2) 0.267
Micro-VI (%) 49 (62) 21 (48.8) 0.183
BCLC
0/A 40 (50.6) 16 (37.2) 0.306
B 23 (29.1) 14 (32.6)
C 16 (20.3) 13 (30.2)
TNM Stage (I/II/III) 18/28/33 11/13/19 0.838
TB 17.5 + 9.9 17.2 + 10.7 0.859
ALT 64.6 + 79.7 53.5 + 63.8 0.433
AST 75.4 + 94 79.6 + 210.2 0.879
ALB 42.4 + 7.4 42.3 + 5.3 0.964
Cirrhosis 49 (62) 28 (65.1) 0.845
Poor Differentiation (%) 44 (55.7) 15 (34.9) 0.037
HBV (%) 75 (94.9) 36 (83.7) 0.333
Child–Pugh grade A (%) 6 (7.6) 3 (7) 1.000
AFP ≥200 (%) 36 (45.6) 19 (44.2) 1.000

PD-L1, programmed death-ligand 1; BCLC, Barcelona Clinic Liver Cancer; TNM, tumor-node-metastasis; TB, total bilirubin; ALT, alanine transaminase; AST, aspartate transaminase; ALB, albumin; HBV, hepatitis B virus; AFP, alpha fetoprotein.