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Annexin-V Assay in OTS514-treated colorectal cancer cells.
| OTS514 (nM) | Early apoptosis (%) | Late apoptosis (%) | ||
|---|---|---|---|---|
| 0 | 20 | 0 | 20 | |
| SW48 | 17.6 ± 0.6 | 29.5 ± 0.4** | 4.6 ± 0.2 | 8.8 ± 0.9** |
| HCT116 | 6.5 ± 0.2 | 15.1 ± 1.4** | 3.5 ± 0.2 | 14.8 ± 2.4** |
| LoVo | 11.1 ± 0.8 | 24.7 ± 3.1** | 12.5 ± 0.8 | 14.9 ± 2.9 |
**p < 0.01.
