Figure 2.

Administered cumulative dose intensities for drugs on T15 versus T16, by risk arm. The only significant differences (***P<0.0001) in dose intensities with more than a 10% difference between protocols were for cyclophosphamide and cytarabine (standard-risk arms) and for mercaptopurine (both risk arms), all of which were higher on T15 than on T16 (see Online Supplementary Table S3 for details on all drugs). Bars and whiskers indicate medians and median absolute deviations among each patient population. There was a total of 16 statistical comparisons, thus the Bonferroni significance threshold=0.003.