TABLE 1.
Sample summary in discovery panel and replications.
| High myopia group | Control group | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Analysis | Sample size | Age | Age of onset | Male/Female | Refraction (Diopter) | Axial length (mm) | Familial/Sporadic | Sample size | Age | Male/Female | ||
| Right eyes | Left eyes | Right eyes | Left eyes | |||||||||
| GWA study | 507 | 36.7 ± 0.7 | 14.7 ± 0.5 | 190/317 | −14.95 ± 0.27 | −14.62 ± 0.30 | 29.76 ± 0.12 | 29.55 ± 0.14 | 91/416 | 294 | 22.15 ± 0.3 | 166/128 |
| Verification | 476 | 36.8 ± 0.7 | 14.3 ± 0.5 | 177/299 | −15.05 ± 0.28 | −14.57 ± 0.31 | 29.83 ± 0.12 | 29.55 ± 0.14 | 77/399 | 275 | 22.26 ± 0.3 | 152/123 |
| KMUH | 991 | 21.21 ± 0.12 | 10.79 ± 0.08 | 659/306 | −7.65 ± 0.05 | −7.39 ± 0.05 | — | — | 331/435 | 1,025 | 21.38 ± 0.19 | 874/146 |
| SPPH | 615 | 36.03 ± 0.6 | — | 249/353 | −9.71 ± 0.23 | −9.50 ± 0.22 | 26.87 ± 0.15 | 26.71 ± 0.13 | — | — | — | — |
Data are Mean ± SEM; mm, millimeter.