Table 2.

Description of measures included in the parent/participant perspective questionnaire

Measure	Outcome
Patient/Parent Global Impression Scales for Severity and Improvement	Severity and improvement in OCD and tic symptoms, based on a standard 7-point Likert scale derived from the Clinician Global Impression scales.53
PANS rating scale	Severity and change in PANS/PANDAS symptoms38
National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS) measures	Patient-reported measures of (1) global health and (2) pain intensity, including 8 items overall.54 55
Treatment expectancy	Two items assuming assignment of the participant to either placebo or active drug. Rated on a 7-point Likert scale, previously linked with treatment response and lower attrition in a clinical trial of CBT for youth with OCD.56
Self-reported OCD severity	Self-report CY-BOCS, combining scores for obsessions and compulsions to generate a total score out of 20, consistent with recommendations based on a recent study of CY-BOCS construct validity.57
Self-report and parent-report versions of the Obsessive Compulsive Inventory-Child Version	21-item self-report measure that assesses obsessive-compulsive symptoms in children and adolescents aged 7–17 years over the preceding month.58
Postvisit questionnaire items	Likert-scale and open-ended items querying participant experiences with virtual visits and trial participation, based on previous work but tailored to this current study.59

CBT, cognitive–behavioural therapy; CY-BOCS, Children’s Yale-Brown Obsessive Compulsive Scale; OCD, obsessive–compulsive disorder; PANDAS, paediatric autoimmune neuropsychiatric disorder associated with streptococcal infections; PANS, paediatric acute-onset neuropsychiatric syndrome.