Table 1.
Baseline characteristics of the study subjects
| Parameter | Patients | F(χ2) | P value | ||
| DM | DLEAD | DCLI | |||
| n (%) | 27 (26.2) | 46 (44.7) | 30 (29.1) | ||
| Male/female (n) | 14/13 | 28/18 | 16/14 | 0.715 | 0.699 |
| Age (years) | 44.41±11.40 | 57.07±10.19 | 64.53±10.46 | 26.133 | <0.001 |
| BMI (kg/m2) | 22.13±2.93 | 23.54±3.60 | 23.19±2.74 | 1.302 | 0.277 |
| Course (%) | 26.036 | <0.001 | |||
| <5 years | 23 (85.2) | 15 (32.6) | 8 (26.7) | ||
| 5–10 years | 2 (7.4) | 11 (23.9) | 4 (13.3) | ||
| ≥10 years | 2 (7.4) | 18 (39.1) | 17 (56.7) | ||
| Smoking (%) | 7 (25.9) | 15 (32.6) | 6 (20.0) | 1.145 | 0.564 |
| Current | 5 | 14 | 5 | ||
| Former | 2 | 1 | 1 | ||
| Never | 20 | 31 | 24 | ||
| Hypertension (%) | 7 (25.9) | 19 (41.3) | 18 (60.0) | 8.314 | 0.016 |
| Hyperlipidemia (%) | 6 (22.2) | 23 (50.0) | 13 (43.3) | 6.264 | 0.044 |
| Family history (%) | 3 (11.1) | 19 (41.3) | 5 (16.7) | 9.936 | 0.007 |
| 2hPBG (mM) | 10.51±4.41 | 11.67±3.91 | 9.75±5.12 | 1.616 | 0.205 |
| GLU (mM) | 7.65 (5.23–14.46) | 7.11 (4.92–10.13) | 9.41 (6.39–14.97) | 2.699 | 0.259 |
| HbA1c (mmol/mol) | 9.70 (7.21–12.41) | 9.25 (8.20–11.20) | 7.80 (7.10–9.50) | 4.205 | 0.122 |
| CRP (mg/L) | 1.12 (0.57–5.66) | 2.40 (0.85–7.54) | 21.35 (2.63–62.07) | 12.601 | 0.002 |
| TG (mM) | 1.40 (1.06–2.53) | 1.57 (0.94–2.44) | 1.61 (1.28–2.77) | 2.388 | 0.303 |
| CHOL (mM) | 4.87 (3.91–5.55) | 4.22 (3.22–5.24) | 3.77 (2.93–4.58) | 7.465 | 0.024 |
| HDL-C (mM) | 1.09 (0.82–1.30) | 0.94 (0.76–1.17) | 0.84 (0.72–0.97) | 5.832 | 0.054 |
| LDL-C (mM) | 3.09±0.88 | 2.67±0.94 | 2.43±1.05 | 3.237 | 0.044 |
| WCC (×109/L) | 6.66 (5.31–9.02) | 7.61 (6.50–9.50) | 8.74 (7.21–11.71) | 7.171 | 0.028 |
| Hb (g/L) | 138.6 (128.5–145.5) | 127.5 (113.0–143.0) | 106.0 (85.0–118.5) | 21.340 | <0.001 |
Data are mean±SD or median (IQR).
BMI, body mass index; CHOL, cholesterol; CRP, C reactive protein; DCLI, diabetic critical limb ischemia; DLEAD, diabetic lower extremity arterial disease; DM, diabetes mellitus; GLU, glucose; Hb, hemoglobin; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; 2hPBG, 2-hour postprandial blood glucose; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride; WCC, white cell count.