Cell viability of osteoarthritis (OA) patient chondrocytes after
treatment with different concentrations of interleukin-1β (IL-1β) for 24
hours (A), n = 6. (B) ELISA
was used to measure the HMGB1 levels in chondrocytes stimulated with
IL-1β (10 ng/mL) over the time course, n = 6 for each
time point. (C) Viability of chondrocytes after treatment
with glycyrrhizin at indicated concentrations for 24 hours,
n = 6. (D) Viability of chondrocytes
after co-treatment of IL-1β (10 ng/mL) and glycyrrhizin at indicated
concentrations for 24 hours (n = 6). All the
experiments were repeated independently 3 times.
#P < 0.05,
##P < 0.01 compared with IL-1β
treatment. *P < 0.05, **P <
0.01, ***P < 0.001 compared with NC.