Table 4.

Spearman’s Rank Correlation Coefficients for Early OA ^a .

	IL6	IL8	MMP1	MMP3	MMP13	TIMP1	TIMP2	Adiponectin	COMP
IL6	ρ = 1.000
IL8	ρ = 0.3526, P ≤ 0.05	ρ = 1.000
MMP1	ρ = 0.5288, P ≤ 0.001	ρ = 0.5790, P ≤ 0.001	ρ = 1.000
MMP3	ρ = 0.2734,P = 0.088	ρ = 0.4013, P ≤ 0.05	ρ = 0.5801, P ≤ 0.001	ρ = 1.000
MMP13	ρ = 0.649, P ≤ 0.001	ρ = 0.1706, P = 0.286	ρ = 0.5192, P ≤ 0.001	ρ = 0.1831, P = 0.258	ρ = 1.000
TIMP1	ρ = −0.1476, P = 0.357	ρ = 0.3097, P ≤ 0.05	ρ = 0.1481, P = 0.355	ρ = 0.2253, P = 0.162	ρ = −0.2221, P = 0.163	ρ = 1.000
TIMP2	ρ = 0.0960, P = 0.551	ρ = −0.6897, P ≤ 0.001	ρ = −0.2833, P = 0.073	ρ = −0.2195, P = 0.174	ρ = 0.06475, P = 0.688	ρ = −0.0199, P = 0.902	ρ = 1.000
Adiponectin	ρ = −0.3559, P = 0.176	ρ = −0.0529, P = 0.846	ρ = −0.4706, P = 0.066	ρ = −0.3029, P = 0.254	ρ = −0.4296, P = 0.097	ρ = 0.0118, P = 0.966	ρ = −0.1882, P = 0.485	ρ = 1.000
COMP	ρ = −0.0609, P = 0.778	ρ = −0.1787, P = 0.403	ρ = −0.0530, P = 0.806	ρ = −0.1047, P = 0.634	ρ = −0.2336, P = 0.272	ρ = 0.0670, P = 0.756	ρ = 0.2278, P = 0.284	ρ = −0.1235, P = 0.649	ρ = 1.0000

OA = osteoarthritis; IL = interleukin; MMP = matrix metalloproteinase; TIMP = tissue inhibitor of metalloproteinase; COMP = cartilage oligomeric matrix protein.

^aValues are the Spearman’s rank correlation coefficient (ρ). P < 0.05 was considered statistically significant.