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Modulation of apoptosis and autophagy through caspase inhibition. Immunofluorescent detection of Pik3cg and Beclin-1 and apoptosis in micromass cultures after 6 days of cultivation with FMK inhibitor (B, E, H), OPH inhibitor (C, F, I), and control group with DMSO (A, D, G). Positive fluorescent signal in red (A-C) and in green (D-I), nuclei in blue (DAPI). Scale bar = 100 µm. Results shown are typical from 3 replicates.
